broadinstitute.org, as data

# **Broad is** accelerating discoveryWe are fostering a diverse research community engaged in innovative chemical biology and therapeutic research./chemical-biology-and-therapeutics-scienceGenome regulation, cellular circuitry, and epigenomicsOur scientists are charting the vast landscape of molecular elements that define and regulate the cell./genomeregulation-cellcircuitry-epigenomicsinteracting with antigen-presenting cells (blue) under a scanning electron microscope.")Researchers across Broad are defining the immune cells and pathways that regulate physiologic and pathologic processes.Medical and population geneticsAn array of scientists here are collaborating to establish genomic variations' roles in human traits and disorders./medical-population-geneticsOur researchers aim to decipher the metabolic basis of rare and common human diseases., with the C4 protein (in green) deposited on synapses. ")We are characterizing the genetic and mechanistic basis of brain health and brain diseases.which pumps phosphate into a cell and leaves it vulnerable to inhibiting phosphate export. Cell nuclei are shown in blue.")Our scientists are probing the mechanisms of cancer and applying this knowledge to enable precision cancer medicine.and fibroblasts (yellow). DNA is stained blue.")By applying a variety of tools and technologies, researchers here are working to reduce the burden of cardiovascular disease.By uncovering the biology underlying heart disease, diabetes, cancer, and more, we’re helping to develop effective new treatments that target the root causes of these chronic diseases., proinsulin (magenta), nuclei (cyan).")Our researchers study the cellular roles and physiological impacts of genes associated with type 2 diabetes.Infectious disease and the microbiomeResearchers across the institute are working to understand infectious diseases, antibiotic resistance, and the human microbiome./infectious-disease-microbiome