elifesciences.org, as data

### Highlights## Signals for retinal developmentSynchronous waves of activity in the developing retina of postnatal mice potentially involve purinergic signalling triggered by apoptotic retinal ganglia.Michael A Savage, Cori Bertram ... Evelyne Sernagor## Publish-review-curate at eLifeeLife is rethinking how research is reviewed and published.Timothy E Behrens, Yamini Dalal, Diane M Harper## Insights into synaptic dysfunctionLRRK2, a protein linked to Parkinson’s disease, interacts with an actin-binding protein, drebrin, to regulate synaptic function and has a role in BDNF-dependent synaptic modulation.Giulia Tombesi, Shiva Kompella ... Elisa Greggio## Science under threatHow should the scientific community respond to ideological attacks on science?> We liked the idea of having an open 'conversation' with the reviewers during the process, and having the chance to polish the manuscript by following the editors and reviewers’ recommendations without the threat ofPatrick Allard, UCLA and eLife authorResearchers explain why they published in eLife### Latest research1. Structural Biology and Molecular Biophysics2. Chromosomes and Gene ExpressionA simulation study shows that metrics suggested to assess replication studies are useful in the translation context, but researchers need to clarify their translation goals a priori.Separate prefrontal output channels preferentially track anxiety, exploration, and social preference, revealing how emotional context is organized into adaptive behavior.Adolescent suicidality is linked to riskier choices through stronger attraction to high-reward gambles and blunted mood responses to safe rewards.### Magazine1. Epidemiology and Global Health2. See more Magazine articles### Categories1. Biochemistry and Chemical Biology4. Chromosomes and Gene Expression5. Computational and Systems Biology8. Epidemiology and Global Health11. Immunology and Inflammation13. Microbiology and Infectious Disease