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While these benefits make a compelling case for continued IS research, the pursuit of AI driven opportunities in tourism development must be balanced against emerging concerns. Critical issues such as ethics, fairness, and data protection have become incre asingly prominent (Vlačić et al., 2021).As tourists increasingly weave smartphones and AI into their travel experiences and daily routines, this early phase of AI development offers unique opp ortunities to expand both theoretical and practical understanding of IS in tourism .This special issue invites contributions that# Page 2advance understanding of IS applications and methodologies within tourism contextsin the era of AI . We welcome research addressing the following areas, though submissions are not limited to these topicsSmart tourism experience, smart tourism destinationSmart business ecosystems and platformPsychological and behaviouralin tourism products / servicesCross cultural differences and regional disparities in adoption of ISAI powered tourist experienceSocietal, cultural, and ethical issues related to AI powered tourism marketing practicesAssessment of the positive and negative implications of AI developments in tourism marketingthe machine learning methods for prediction and feature engineeringtourists’ d ecision making and choice modelingB ig data and pattern recognition in tourismUnderstanding tourists’ opinions using ISEthical , privacy issue , s ecurity and data protectionThis special issue will be composed of two categoriesof papers: (1) high calibre submissionsthrough an open call for papers and (2) invited submissions that are extended or modified versions of selected papers accepted by the 3 rdFor the latter category, the author(s) is expected to significantly improve the conference paper. Upon submission, a detailed explanation about the differences between the conference paper and the version submitted to this Special Issue